Development of the 2K22 anti-aircraft system began on 8 June 1970. At the request of the Soviet Ministry of Defense, the KBP Instrument Design Bureau in Tula, under the guidance of the appointed Chief Designer A. G. Shipunov [ru], started work on a 30mm anti-aircraft system as a replacement for the 23mm ZSU-23-4.
The initial designs were completed in 1973, with pilot production completed in 1976 at the Ulyanovsk Mechanical Factory. System testing and trials were conducted between September 1980 and December 1981 on the Donguzskiy range. It was officially accepted into service on 8 September 1982 and the initial version, which was designated 2K22/2S6, had four missiles in the ready to fire position (two on each side) and two 2A38 autocannons. The Tunguska entered into limited service from 1984, when the first batteries were delivered to the army.
Variants of the 2K22 system have continued to serve in the Soviet and later Russian armed forces since their initial introduction in 1984. The 2K22 has also been inducted into the armed forces of a number of foreign states, most notably India. The 2K22 has been used in the 2008 South Ossetia war by Russian armed forces.
After a limited production run of the original 2K22, an improved version designated 2K22M/2S6M entered service in 1990. The 2K22M featured several improvements with eight ready-to-fire missiles (four on each side) as well as modifications to the fire control programs, missiles and the general reliability of the system, and improved autocannons, 2A38M.
Tunguska underwent further improvement when, in 2003, the Russian armed forces accepted the Tunguska-M1 or 2K22M1 into service. The M1 introduced the new 9M311-M1 missile, which made a number of changes allowing the 2K22M1 to engage small targets like cruise missiles by replacing the eight-beam laser proximity fuze with a radio fuse. An additional modification afforded greater resistance to infrared countermeasures by replacing the missile tracking flare with a pulsed IR beacon. Other improvements included an increased missile range from 8 to 10 kilometres (5.0 to 6.2 mi), improved optical tracking and accuracy, improved fire control co-ordination between components of a battery and the command post. Overall, the Tunguska-M1 has a combat efficiency 1.3–1.5 times greater than the Tunguska-M.
Improved version with the 2S6M1 combat vehicle on a GM-5975 chassis, using the 9M311-M1 missile (range: 10 kilometres (6.2 mi)) and with an improved fire control system. Passed state trials and entered service with the Russian armed forces on 31 July 2003.
The 2K22 has been used in the 2022 Russian invasion of Ukraine by Ukrainian and Russian forces. In June 2023, Ukraine ordered the repair, refurbishment, and spare parts through the International Fund for Ukraine.