Born in Coeur d'Alene, Idaho, on November 22, 1990, Osweiler was raised by his parents, Kathy and John Osweiler, in Kalispell, Montana. Osweiler attended Flathead High School. Osweiler's older brother, Tanner, played college football in the National Association of Intercollegiate Athletics (NAIA) at Montana Tech in Butte. Their father received scholarship offers to play football at Montana and Montana State but ultimately chose to enter the military out of high school.
Brock Alan Osweiler (born November 22, 1990) is an American former professional football quarterback who played in the National Football League (NFL) for seven seasons. He played college football for the Arizona State Sun Devils and was selected by the Denver Broncos in the second round of the 2012 NFL draft. Osweiler first served as the Broncos' starter during their Super Bowl-winning season in 2015 when he relieved an injured Peyton Manning and helped Denver get the top seed in the AFC heading into the postseason, although Manning resumed his starting duties for the playoffs and eventual Super Bowl 50 victory.
Osweiler chose to attend Arizona State University over scholarship offers from Stanford and Washington State. As a true freshman in 2009, Osweiler played in six games with one start. He became the first true freshman to start a game for the Sun Devils since Jake Plummer in 1993. He finished the season completing 24 of 55 passes for 249 yards with two touchdowns and two interceptions. As a sophomore in 2010, he again played in six games with one start. For the season he completed 62 of 109 passes for 797 yards, five touchdowns and no interceptions. As a junior in 2011, he took over as the Sun Devils starting quarterback after the retirement of Steven Threet. He finished the season with 4,036 yards and 26 touchdowns.
Osweiler played both football and basketball; football was the dominant sport in Montana, so Osweiler traveled to neighboring states to play for Amateur Athletic Union (AAU) basketball teams in Portland, Oregon, and Seattle, Yakima, and Spokane, Washington. In 2006, after his freshman year of high school, he committed to Gonzaga University in Spokane to play basketball, but later decided to focus on playing college football. As a senior, he was the 2008–2009 Gatorade Player of the Year in football for Montana after he completed 189 of 303 passes for 2,703 yards and 29 touchdowns; he also rushed for 700 yards on 162 carries with 13 touchdowns.
In a Week 7 win against the San Francisco 49ers, Osweiler attempted one incomplete pass. During a Week 10 41–17 win against the Raiders, Osweiler completed 2 of 5 passes for 13 yards. During the Broncos Week 15 22–10 win against the San Diego Chargers, Osweiler had two incomplete passes. Osweiler threw his first career touchdown against the Raiders on December 28, 2014.
Osweiler married Erin Costales in February 2015. The couple have two children.
Against the Kansas City Chiefs on November 15, 2015, Osweiler took over for Peyton Manning, who was benched after throwing four interceptions and posting a passer rating of 0.0. The Broncos later announced that Osweiler would start in place of the injured Manning the following week against the Chicago Bears. In his first start on his 25th birthday, he completed 20 out of his 27 passes for 250 yards with two touchdowns and a 127.1 passer rating in a 17–15 win over the Bears, becoming the first player to start and win his first career game on his birthday. He was named the AFC Offensive Player of the Week for his performance against the Bears. Osweiler was presented the game ball after the game by head coach Gary Kubiak. The next day, it was announced that Osweiler would start the following week against the New England Patriots. On November 29, 2015, Osweiler led the Broncos to a win over the then-undefeated Patriots in overtime, 30–24. He completed 23 of 42 passes for 270 yards, a touchdown, and an interception. Osweiler started his third consecutive game for the injured Manning during Week 13 against the San Diego Chargers. He finished the game with 16 of 26 completions (61.5%) for 166 passing yards, a touchdown, and an interception. The following week, Osweiler suffered his first loss in a 15–12 defeat to the Oakland Raiders. He capped the game off with a career-high 51 attempts, completing 35 of them for 308 yards.
On December 15, it was announced that Osweiler would start his fifth consecutive game against the Pittsburgh Steelers despite the fact that Manning had returned to practice. During the game Osweiler completed 21 of 44 passes for 296 yards, three touchdowns, and an interception. He also carried the ball 5 times for 19 yards and a seven-yard touchdown, but the Broncos ultimately lost 34–27. In Week 16, Osweiler started his sixth consecutive game against the Cincinnati Bengals, completing 27 of 39 attempts for 299 yards and one touchdown in a 20–17 overtime win. In the Broncos' regular-season finale, on January 3, Osweiler was replaced by Manning in the third quarter after throwing two interceptions and fumbling once. Manning led the Broncos to a 27–20 win over the Chargers and helped the Broncos secure the top seed in the AFC. On January 7, 2016, the team announced Osweiler suffered a low-grade strain to the medial collateral ligament of his right knee during a game against the San Diego Chargers.
Osweiler finished the 2015 season completing 170 completions out of 275 attempts (61.8%) for 1,967 yards for 10 touchdowns and 6 interceptions while having an 86.4 quarterback rating. He also rushed for 61 yards on 21 attempts for an additional touchdown. On February 7, 2016, Osweiler was active as the backup quarterback as the Broncos won Super Bowl 50 over the Carolina Panthers by a score of 24–10. Despite Osweiler not seeing any playing time in the postseason, his 5–2 record as a starter in the 2015 regular season while Manning was sidelined with a foot injury was instrumental in helping Denver capture the top seed in the AFC and earning home field advantage over the New England Patriots in the AFC Championship Game.
On March 9, 2016, Osweiler signed a four-year, $72 million contract ($37 million guaranteed) with the Houston Texans.
In his Texans' debut on September 11, 2016, Osweiler passed for 231 yards, two touchdowns, and an interception in the 23–14 victory over the Chicago Bears. Despite his strong start, he began to struggle as the season progressed. During a Week 7 road game against his former team, the Denver Broncos, Osweiler had a total of three fumbles with one lost as the Texans were defeated 27–9. During Week 12 against the San Diego Chargers, Osweiler threw no touchdowns and three interceptions as the Texans lost 21–13. However, he did contribute a 1-yard rushing touchdown.
On March 9, 2017, Osweiler was traded to the Cleveland Browns along with the Texans' 2017 sixth-round pick and 2018 second-round pick in exchange for the Browns' 2017 fourth-round compensatory pick. This trade was termed by ESPN's Adam Schefter as possibly the most creative trade in NFL history. The move allowed Cleveland to absorb some of Osweiler's cap from Houston in exchange for draft picks, one of the first trades of its kind. On September 2, 2017, Osweiler was released by the Browns after the team named rookie DeShone Kizer as the starter.
On September 2, 2017, Osweiler signed a one-year contract with the Broncos after backup quarterback Paxton Lynch sustained a shoulder injury. His contract was worth the league-minimum $775,000, leaving the Browns to pay the remaining $15.25 million of Osweiler's $16 million guaranteed.
On March 23, 2018, Osweiler signed with the Miami Dolphins, reuniting him with his former Broncos offensive coordinator Adam Gase.
On October 16, 2019, Osweiler announced his retirement from the NFL. Osweiler joined ESPN in 2022 as a college football analyst.
In 2024, it was announced that Osweiler would serve as an ambassador for SHARx, a patient advocacy company for uninsured and underinsured Americans. “This is a passion of mine because it hits so close to home. Those closest to me have experienced the loss of loved ones because the high price of the drugs they needed made access impossible," Osweiler said in a statement announcing his ambassadorship.
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