History of Dengue fever in Timeline

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Dengue fever

Dengue fever, a mosquito-borne viral disease common in tropical and subtropical regions, presents with varying severity. Many infections are asymptomatic or mild. Symptomatic cases, appearing 3-14 days post-infection, involve high fever, headache, vomiting, muscle/joint pain, itching, and rash. Recovery usually occurs within 2-7 days. A small percentage of cases progress to severe dengue, characterized by bleeding, low platelet count, plasma leakage, and dangerously low blood pressure.

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1953: First Report of Severe Hemorrhagic Form of Dengue in the Philippines

In 1953, the severe hemorrhagic form of dengue was first reported in the Philippines.

1998: Awareness month in the Philippines

Since 1998, The Philippines has an awareness month in June.

2010: International Anti-Dengue Day agreed upon

In 2010, the idea for International Anti-Dengue Day was first agreed upon.

2010: Increase in dengue cases reported by WHO

The World Health Organization (WHO) recorded a ten-fold increase in dengue cases between 2010 and 2019.

2011: First International Anti-Dengue Day event

In 2011, the first International Anti-Dengue Day event was held in Jakarta, Indonesia.

2012: International Anti-Dengue Day event in Yangon, Myanmar

In 2012, an International Anti-Dengue Day event was held in Yangon, Myanmar.

2013: Global burden of dengue estimated

A study estimated that in 2013 the global burden of dengue amounted to US$8.9 billion.

2013: International Anti-Dengue Day event in Vietnam

In 2013, an International Anti-Dengue Day event was held in Vietnam.

2013: Estimated Dengue Infections

In 2013, approximately 390 million dengue infections occurred, with 500,000 cases developing severe symptoms and 25,000 resulting in death.

2015: Dengvaxia availability

In 2015, Dengvaxia (formerly CYD-TDV) became available and was approved for use in the US, EU, and some Asian and Latin American countries.

2016: Dengvaxia availability

In 2016, Dengvaxia became commercially available, but its use was recommended only for preventing re-infection in individuals previously infected with dengue.

2019: Ongoing efforts to make International Anti-Dengue Day a global event

As of 2019, efforts are ongoing to make International Anti-Dengue Day a global event.

2019: Increase in dengue cases reported by WHO

The World Health Organization (WHO) recorded a ten-fold increase in dengue cases between 2010 and 2019.

December 2022: Qdenga approved for use in the European Union

In December 2022, Qdenga (formerly TAK-003) was approved for use in the European Union after completing clinical trials.

2022: Qdenga availability

In 2022, Qdenga became available and suitable for adults, adolescents, and children from four years of age.

March 2023: Dengue Endemicity

As of March 2023, dengue is endemic in more than 100 countries across nearly every continent, excluding Antarctica.

October 2023: First confirmed symptomatic case of locally acquired dengue in California

In October 2023, the first confirmed symptomatic case of locally acquired dengue in the US was identified in California.

2023: Dengue infections reported worldwide

During 2023, over 5 million dengue infections were reported, accompanied by more than 5,000 dengue-related deaths.

March 2024: Dengue vaccines available

As of March 2024, two vaccines, Dengvaxia and Qdenga, exist to provide protection against dengue infection.

July 2024: No specific antiviral treatment available for dengue fever

As of July 2024, there is no specific antiviral treatment available for dengue fever.