Dengue fever, a mosquito-borne viral disease common in tropical and subtropical regions, presents with varying severity. Many infections are asymptomatic or mild. Symptomatic cases, appearing 3-14 days post-infection, involve high fever, headache, vomiting, muscle/joint pain, itching, and rash. Recovery usually occurs within 2-7 days. A small percentage of cases progress to severe dengue, characterized by bleeding, low platelet count, plasma leakage, and dangerously low blood pressure.
In 1953, the severe hemorrhagic form of dengue was first reported in the Philippines.
Since 1998, The Philippines has an awareness month in June.
In 2010, the idea for International Anti-Dengue Day was first agreed upon.
The World Health Organization (WHO) recorded a ten-fold increase in dengue cases between 2010 and 2019.
In 2011, the first International Anti-Dengue Day event was held in Jakarta, Indonesia.
In 2012, an International Anti-Dengue Day event was held in Yangon, Myanmar.
A study estimated that in 2013 the global burden of dengue amounted to US$8.9 billion.
In 2013, an International Anti-Dengue Day event was held in Vietnam.
In 2013, approximately 390 million dengue infections occurred, with 500,000 cases developing severe symptoms and 25,000 resulting in death.
In 2015, Dengvaxia (formerly CYD-TDV) became available and was approved for use in the US, EU, and some Asian and Latin American countries.
In 2016, Dengvaxia became commercially available, but its use was recommended only for preventing re-infection in individuals previously infected with dengue.
As of 2019, efforts are ongoing to make International Anti-Dengue Day a global event.
The World Health Organization (WHO) recorded a ten-fold increase in dengue cases between 2010 and 2019.
In December 2022, Qdenga (formerly TAK-003) was approved for use in the European Union after completing clinical trials.
In 2022, Qdenga became available and suitable for adults, adolescents, and children from four years of age.
As of March 2023, dengue is endemic in more than 100 countries across nearly every continent, excluding Antarctica.
In October 2023, the first confirmed symptomatic case of locally acquired dengue in the US was identified in California.
During 2023, over 5 million dengue infections were reported, accompanied by more than 5,000 dengue-related deaths.
As of March 2024, two vaccines, Dengvaxia and Qdenga, exist to provide protection against dengue infection.
As of July 2024, there is no specific antiviral treatment available for dengue fever.
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