Colombia and Mexico have maintained diplomatic relations since 1821, with Colombia being the first Latin American country to recognize Mexico's independence. Both nations share membership in several regional and international organizations, including the Association of Caribbean States, Community of Latin American and Caribbean States, Latin American Integration Association, Organization of American States, Organization of Ibero-American States, Pacific Alliance, and the United Nations. This shared membership highlights their cooperative relationship across various political, economic, and social domains within Latin America and on a global scale.
In 1998, Colombia and Mexico signed several agreements including a Tourist Cooperation Agreement, an Agreement for the Exchange of Non-Judicialized Information, an Agreement for Mutual Recognition of Certificates of Studies, Titles and Academic Degrees of Higher Education and an Agreement of Cooperation on Legal Matters.
In July 2021, Colombian Vice-President and Foreign Minister Marta Lucía Ramírez visited Mexico and met with her counterpart, Marcelo Ebrard, to reaffirm their commitment to strengthening bilateral relations.
In September 2023, Mexican President Andrés Manuel López Obrador visited Cali, Colombia, to attend a Latin-American and Caribbean Conference on drugs and met with Colombian President Gustavo Petro to discuss the peace process in Colombia.
In 2023, trade between Colombia and Mexico totaled US$5.6 billion. Colombia's main exports to Mexico included coal, crude oil, instant coffee, and automobile parts, while Mexico's main exports to Colombia included flat screen TVs, pure petroleum oil for tank-car, ship-tank or auto-tanks; corrugated rods or bars for reinforcement, for cement or concrete; shampoos; milk powder or pills; tequila and malt beer.
In October 2024, President Petro travelled to Mexico to attend the inauguration of President Claudia Sheinbaum.
In December 2024, President Petro returned to Mexico and met with President Sheinbaum.
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