Look Up Child debuted at No. 3 on the US Billboard 200 with 115,000 album-equivalent units, of which 103,000 were pure album sales. It is the highest-charting album by Daigle and the highest-charting Christian album overall since Hard Love by Needtobreathe reached No. 2 on the chart in 2016. The album became the highest-charting Christian album by a woman on the Billboard 200 since LeAnn Rimes' You Light Up My Life peaked at No. 1 in 1997. The album won Best Contemporary Christian Music Album at the 2019 Grammy Awards.
Daigle started singing in her choir and continued to lead the choir at LSU. She tried out for American Idol in 2010 and 2012 after she was encouraged by her family to compete in the singing competition. She was cut just before the final 24 contestants in 2010, and she did not make it to Hollywood in 2011. She made it to the Hollywood round in 2012, but was cut in the first Las Vegas round.
Daigle was asked to sing background vocals on an EP for a local band called "The Assemblie" and the EP was briefly the most sold album in the US iTunes Store. After the release of the EP, Centricity Music invited her to attend a workshop. When the singer for the main event at the workshop became ill, she was asked to fill in. This led to her singing on the Jason Gray single "Nothing is Wasted". Centricity Music signed her on the label in 2013.
Her first single, "Light of the World" came from the 2013 album Christmas: Joy To The World, a collection of holiday songs from various Centricity artists. Serving as Daigle's solo introduction to the Christian music scene, the single garnered an initial fan-base and much attention for Daigle. That year, Daigle was asked to be a part of the Morning Rises Fall Tour with Aaron Shust and Mikeschair. Daigle released the EP How Can It Be in September 2014.
She made her debut on North Point InsideOut's album, Hear, where she recorded "Close" and "You Alone" live at North Point Community Church in Alpharetta, Georgia. She later appeared on North Point Music's album North Point Beginnings where she recorded "It is Well" in 2015.
Daigle's debut full-length album, How Can It Be was released April 14, 2015, debuting at No. 1 on the Billboard Christian Albums Chart. The album also broke Top 20 on the Billboard Top Albums Chart for all genres (No. 16). Daigle was named one of Christian music's break-out artists, and her album's first single "How Can It Be" was named by iTunes as one of the Top Christian songs of 2014. The single "How Can It Be" also reached Top 10 at NCA, AC Monitored, and AC Indicator. As a whole, the album logged six weeks at No. 1 on the Billboard Christian Albums Chart. Eighteen months after its release, How Can It Be achieved Gold Record status. The album is certified platinum.
On June 1, 2015, Daigle accepted her first award, Worship Song of the Year, for her single "How Can It Be" at the K-Love Awards. This was also the first K-Love Fan Award for her label, Centricity Music. The album How Can It Be won the 2016 Billboard Award for Top Christian Album and was nominated for the 2016 Grammy Award for Best Contemporary Christian Music Album. Along with being named Best New Artist at the 2015 Dove Awards, Daigle earned awards for Song of the Year and Contemporary Song of the Year (for "How Can It Be). At the next year's ceremony, she took home the top honor of Artist of the Year, plus Songwriter of the Year, and Contemporary Recorded Song of the Year (for "Trust in You"). That year she also won two K-Love Fan Awards, for Artist of the Year and Female Artist of the Year. She received another Grammy nomination in 2017, for Best Contemporary Christian Music Performance/Song, for "Trust in You". Daigle won Female Artist of the Year at the K-Love Fan Awards in 2017 for the second year in a row.
The album's overall success resulted in the release of How Can It Be: Deluxe Edition in May 2016. The deluxe version features the original album's tracks, along with two new songs, acoustic versions of singles "First" and "Come Alive", and a live performance version of "How Can It Be".
In October 2016, Daigle released her first Christmas album, Behold: A Christmas Collection, and reached No. 29 on the Billboard 200. In 2017, she was featured in the song "Hard Love" by Needtobreathe for The Shack. Daigle co-wrote and performed "Almost Human", the only original song, on the Blade Runner 2049 soundtrack. The album, produced by Michael Hodges, Kayla Morrison and Ashley Culp, reached No. 1 on the Billboard Soundtrack Sales Charts.
On October 21, 2016, Daigle released Behold: A Christmas Collection, a Christmas album. Three singles were released to Christian radio on November 25, 2016: "Jingle Bells", "Have Yourself a Merry Little Christmas," and "What Child Is This", with "O Holy Night" released to Christian radio the following year, November 24, 2017, and "Winter Wonderland" released the following year, October 19, 2018.
The album debuted at No. 77 on the US Billboard 200 on November 12, 2016, peaking at No. 29 on December 17, 2016. The album debuted at No. 18 on the US Billboard Christian Albums Chart on November 5, 2016, reaching No. 1 on December 31, 2016.
In 2017, Daigle was chosen to sing, "Almost Human", for the Blade Runner 2049: Original Motion Picture Soundtrack.
"You Say" was released on July 13, 2018, as the lead single for her third studio album, Look Up Child. The song was released to Christian radio on July 9. The album was also available for pre-order. It was released on September 7, 2018, via Centricity Music. It was her first studio album in three years and served as a follow-up to her debut studio album, How Can It Be (2015).
Daigle performed as part of Austin City Limits in 2019. She sang the national anthem at the 2020 College Football Playoff National Championship on January 13, 2020.
As of January 2019, the album has sold 208,000 copies in the U.S.
"You Say" reached No. 1 on the Hot Christian Songs chart, where it has spent 60 weeks at No. 1, beating "Something in the Water" by Carrie Underwood for the longest reign by any solo artist in the chart's history. After becoming a huge Christian radio success (peaking at No. 1 on multiple different charts, including the Christian Airplay, where it spent 17 weeks at No. 1 ), the song was released to mainstream radio on January 15, 2019 by Warner Bros. From there, it reached the Adult Top 40, Adult Contemporary, and Mainstream Top 40 charts. It was the second biggest Christian song of 2018, according to Billboard. It has further reached a peak No. 29 on the Billboard Hot 100. "You Say" won the 2019 Grammy Award for Best Contemporary Christian Music Performance/Song.
In late 2016, Daigle headlined her first tour, A Night With Lauren Daigle, which sold out. She joined for King and Country on their holiday tour later in the year. She was part of the Outcry Tour again in early 2017.