Ricin is a highly toxic protein found in the seeds of the castor oil plant. It's particularly potent when injected, with a small amount being lethal to mice. Oral exposure is less toxic, but still dangerous in larger doses. Ricin is classified as a lectin, meaning it binds to carbohydrates.
In 1903, the US explored ricin's military use but faced limitations due to the Hague Convention's ban on poisoned weapons.
Peter Hermann Stillmark, credited with the first isolation of ricin in 1888, died in 1923.
In 1971, Soviet dissident Aleksandr Solzhenitsyn experienced ricin-like symptoms after an encounter with KGB agents.
Ricin was designated as a Schedule 1 controlled substance under the Biological Weapons Convention of 1972.
In 1978, Bulgarian defector Vladimir Kostov survived a ricin attack, likely due to his body developing antibodies after initial exposure.
In 1978, Bulgarian dissident Georgi Markov was assassinated using a ricin-laced pellet, a case linked to Bulgarian secret police.
In 1997, ricin's status as a controlled substance was further reinforced under the Chemical Weapons Convention.
In 2005, the US military developed an antidote shown to be effective in mice and had undergone some human testing.
In 2006, an antidote for ricin poisoning was developed by the UK military, but hadn't yet been tested on humans.
In May 2013, letters containing ricin were sent to NYC Mayor Michael Bloomberg and President Barack Obama, leading to the arrest and conviction of Shannon Richardson.
The 2013 film "The Good Mother" depicted a case of Munchausen by proxy involving ricin poisoning.
In 2013, a woman in the US survived after ingesting 30 castor beans, highlighting the potential for survival in such cases.
In the 2014 film "The Interview," a transdermal patch containing ricin is employed as part of a fictional CIA operation to assassinate North Korean leader Kim Jong-un.
In September 2015, Mohammed Ali was sentenced to eight years in prison for attempting to buy ricin over the dark web.
In 2015, opposition politician Boris Nemtsov was assassinated near the Kremlin in Moscow.
In October 2018, two letters suspected of containing ricin were sent to The Pentagon, targeting Secretary of Defense James Mattis and Admiral John Richardson.
German police thwarted a planned ricin attack in 2018.
In July 2019, a letter containing ricin was found at Pelican Bay State Prison, but no harmful exposures were reported.
In 2019, the RiVax vaccine against ricin was undergoing clinical trials with promising results in animal and human tests.
In 2020, reports emerged about a Russian agent allegedly carrying ricin into Prague to target Czech politicians, sparking controversy and denial from Russia.
German police thwarted a planned ricin attack in 2023.