Chloe Cole is an American activist known for her opposition to gender-affirming care for minors, advocating for bans on such care after her own detransition. She began transitioning at age 12, undergoing puberty blockers, testosterone treatments, and a double mastectomy by age 15. Experiencing mental health challenges, including hallucinations, and subsequently converting to Christianity, she began detransitioning at 16. Cole has since become a prominent voice, aligning with conservative politicians and appearing in media outlets to share her experiences and advocate against gender-affirming treatments for minors.
On July 27, 2004, Chloe Cole was born. She would later become an activist opposing gender-affirming care for minors.
In February 2018, at the age of 13, Chloe Cole was prescribed the puberty blocker Lupron.
In June 2020, Chloe Cole underwent a double mastectomy at the age of 15.
In May 2022, Chloe Cole began testifying in the United States against medical transition and appeared on Fox News to denounce gender-affirming care for minors, taking a stance against the views of major medical associations.
In mid-July 2022, Chloe Cole started a GoFundMe campaign called "Imperfectly Me", which aimed at providing a platform for detransitioners.
In September 2022, Dawn Ennis, writing for the LGBT newspaper Los Angeles Blade, described Cole as "the poster child for far-right politicians and religious conservatives working to ban gender-affirming care and to prosecute the doctors and parents who support their children's transitions for child abuse."
In October 2022, Chloe Cole was a speaker at a "Rally to End Child Mutilation" hosted by Matt Walsh in Nashville.
On November 9, 2022, Chloe Cole, represented by Harmeet Dhillon and LiMandri & Jonna LLP, filed a 90-day notice of intent to sue Kaiser Permanente along with individual medical professionals involved in her treatment.
In 2022, a similar lawsuit to Cole's was filed in Multnomah County, Oregon, by Camille Kiefel, a 32-year-old woman.
In January 2023, Chloe Cole was one of five panelists who spoke at an event titled "Stolen Innocence: A Panel on the Insidious Ideology Infecting Your Children's Education", about schools allegedly sexually grooming students.
On February 22, 2023, the lawsuit against Kaiser Permanente and individual medical professionals was officially filed in the San Joaquin County Superior Court in Manteca.
In March 2023, Chloe Cole spoke at the Conservative Political Action Conference (CPAC) in Washington D.C., on a panel titled "A Time for Courage".
On April 17, 2023, Chloe Cole spoke at an event at Dartmouth College with Dr. Carrie Mendoza, sharing her views on medical decisions for children and adults.
On December 4, 2024, Chloe Cole spoke at a rally organized by Do No Harm opposing gender-affirming care outside the Supreme Court of the United States during oral arguments for United States v. Skrmetti.
In June 2025, the Supreme Court determined in United States v. Skrmetti that bans on gender-affirming care for minors are constitutional.
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