As early as 1909, musicians such as W. C. Handy performed in clubs on Memphis's Beale Street, considered the epicenter of the blues.
Beginning in 1915, many Black Tennesseans migrated to industrial cities in the Northeast and Midwest due to increasing racial segregation and poor living standards.
On December 30, 1917, Mountain City recorded the lowest temperature in Tennessee at −32 °F (−36 °C).
By 1917, Tennessee became the first state in the nation to effectively ban the sale, transportation, and production of alcohol through a series of laws as part of the Temperance movement.
On July 9, 1918, Tennessee experienced the worst rail accident in U.S. history when two passenger trains collided head-on in Nashville, resulting in 101 fatalities and 171 injuries.
On August 18, 1920, Tennessee became the 36th and final state needed to ratify the Nineteenth Amendment to the United States Constitution, granting women the right to vote.
In 1920, Tennesseans narrowly supported Warren G. Harding over Ohio Governor James Cox in the presidential election.
Since 1925, the Grand Ole Opry, based in Nashville, has broadcast continuously.
In 1927, the Victor recording sessions in Bristol generally mark the beginning of the country music genre.
In 1928, Tennesseans voted for Herbert Hoover over New York Governor Al Smith in the presidential election.
In 1929, the Great Depression began, severely impoverishing much of Tennessee, even by national standards.
On August 9, 1930, Perryville recorded the highest temperature in Tennessee at 113 °F (45 °C).
In 1933, as part of President Franklin D. Roosevelt's New Deal, the Tennessee Valley Authority (TVA) was created to bring electricity, jobs, flood control, improved waterway navigation, agricultural development, and economic modernization to the Tennessee River Valley.
In 1954, the U.S. Supreme Court ruled racial segregation in public schools unconstitutional in Brown v. Board of Education.
In 1955, Oak Ridge High School became the first school in Tennessee to be integrated following the Brown v. Board of Education ruling.
In 1958, the WGC Invitational, a PGA Tour golf tournament, was first held in Memphis.
Between February and May 1960, sit-ins organized by the Nashville Student Movement led to the desegregation of lunch counters in Nashville.
In 1962, the U.S. Supreme Court case Baker v. Carr arose out of a challenge to the longstanding rural bias of apportionment of seats in the Tennessee legislature, establishing the principle of "one man, one vote".
Not until after passage of the Voting Rights Act of 1965 were African Americans able to regain their full voting rights in Tennessee.
In 1966, Howard Baker was first elected, becoming the first Republican U.S. Senator from Tennessee since Reconstruction.
On April 4, 1968, James Earl Ray assassinated civil rights leader Martin Luther King Jr. in Memphis, where King was supporting striking African American sanitation workers.
In 1970, Winfield Dunn was elected as governor of Tennessee.
With the exception of a slump in the 1980s, Tennessee has been one of the fastest-growing states in the nation since 1970, benefiting from the larger Sun Belt phenomenon.
In 1971, the U.S. Supreme Court sided with an activist group in the case of Citizens to Preserve Overton Park v. Volpe, establishing the framework for judicial review of government agencies regarding the construction of Interstate 40 through Memphis' Overton Park.
In 1972, coal production in Tennessee reached its peak.
In 1972, the Knoxville Smokies began play in Minor League Baseball.
In 1976, the Chattanooga Lookouts began play in Minor League Baseball.
In 1978, the Nashville Sounds began play in Minor League Baseball.
In 1978, the U.S. Supreme Court case Tennessee Valley Authority v. Hill, concerning the Tellico Dam's impact on the endangered snail darter fish, led to amendments of the Endangered Species Act.
In 1982, the World's Fair, also known as the Knoxville International Energy Exposition, was held in Knoxville with the theme "Energy Turns the World".
In 1986, Tennessee held a yearlong celebration of the state's heritage and culture called "Homecoming '86".
In 1993, Tennessee experienced a severe winter storm.
In 1996, Tennessee celebrated its bicentennial with "Tennessee 200", opening Bicentennial Mall in Nashville, and hosted the whitewater slalom events at the Atlanta Summer Olympic Games on the Ocoee River in Polk County.
In 1997, the Tennessee Titans played their first season in the National Football League (NFL).
In 1998, the Memphis Redbirds began play in Minor League Baseball.
In 1998, the Nashville Predators played their first season in the National Hockey League (NHL).
Between 2000 and 2010, Tennessee's Hispanic population grew by 134.2%, the third-highest rate of any state.
In 2000, Republican President George W. Bush had a 4% margin of victory.
In the 2000 presidential election, Vice President Al Gore, who had previously served as a Democratic U.S. Senator from Tennessee, failed to carry his home state.
In 2001, the Memphis Grizzlies played their first season in the National Basketball Association (NBA).
In 2002, Tennessee amended its constitution to establish a lottery.
In 2004, Republican President George W. Bush increased his margin of victory in Tennessee from 4% to 14%.
In 2006, the Tennessee state constitution was amended to outlaw same-sex marriage, though this was later invalidated by the U.S. Supreme Court case Obergefell v. Hodges in 2015.
In 2007, Ron Ramsey became the first Republican Speaker of the State Senate since Reconstruction in Tennessee.
On December 23, 2008, the largest industrial waste spill in United States history occurred at TVA's Kingston Fossil Plant, releasing over 1.1 billion gallons of coal ash slurry into the Emory and Clinch Rivers.
In 2009, Chattanooga FC was founded.
In 2011, the Nashville Superspeedway in Lebanon, which previously held Nationwide and IndyCar races, was shut down.
In 2012, the Mississippi Band of Choctaw Indians placed 79 acres in Henning into federal trust.
In 2014, the Tennessee General Assembly created the Tennessee Promise, allowing in-state high school graduates to enroll in two-year post-secondary education tuition-free.
By 2016, Nashville surpassed Memphis to become Tennessee's largest city.
Since 2016, Tennessee has been the most populous state to vote Republican by more than 60% in presidential elections.
Since 2016, Tennessee has had no inheritance tax.
Until 2017, the TBR also operated six public universities in the state; it now only gives them administrative support.
In 2019, Chattanooga Red Wolves SC became a member of the third-tier USL League One.
In 2019, Tennessee received a record of 126 million tourists, making it the 11th-most visited state in the nation.
In 2019, Tennessee reported a total employment of 2,724,545 and a total number of 139,760 employer establishments.
In 2019, about 5.5% of Tennessee's population was foreign-born, with approximately 42.7% being naturalized citizens and 57.3% non-citizens.
According to the 2020 census, 5.7% of Tennessee's population was under age 5, 22.1% were under 18, and 17.1% were 65 or older.
In 2020, 6.9% of the total population in Tennessee was of Hispanic or Latino origin (of any race), up from 4.6% in 2010.
In 2020, Chattanooga FC began playing in the third-tier National Independent Soccer Association.
In 2020, Nashville SC played their first season in Major League Soccer (MLS).
In 2020, Tennessee voted Republican by the largest margin of any state in terms of number of votes.
In 2020, the state's per capita personal income was $30,869, and the median household income was $54,833.
The 2020 United States census reported Tennessee's population at 6,910,840, an increase of 8.90% since the 2010 census.
As of 2021, Tennessee had a gross state product of $418.3 billion.
By 2021, the Hall income tax on most dividends and interest was completely phased out in Tennessee.
In 2021, Tennessee experienced a winter storm.
In 2021, nuclear power produced about 43.4% of Tennessee's electricity. 22.4% was produced from coal, 17.8% from natural gas, 15.8% from hydroelectricity, and 1.3% from other renewables.
In 2021, the Nashville Superspeedway reopened to host the NASCAR Cup Series.
In 2021, the Ohio Valley Conference (OVC) includes the Austin Peay Governors from Clarksville, the UT Martin Skyhawks from Martin, and the Tennessee Tech Golden Eagles from Cookeville.
In 2021, the four-year high school graduation rate in Tennessee was 88.7%.
In July 2022, the Belmont Bruins, previously members of the Ohio Valley Conference (OVC), are set to move to the Missouri Valley Conference (MVC).
According to HUD's 2022 Annual Homeless Assessment Report, there were an estimated 10,567 homeless people in Tennessee.
In 2024, the United States Census Bureau estimated Tennessee's population to be 7.22 million.
In 2025, Ford is expected to have an assembly plant operational in Stanton, Tennessee.