Giacomo "Jack" Della Maddalena was born in September 1996.
Jack Della Maddalena made his professional MMA debut in March 2016, losing to Aldin Bates via TKO. He then lost his next fight against Darcy Vendy via submission.
In September 2021, Jack Della Maddalena won a fight on Dana White's Contender Series 39 against Ange Loosa, securing a UFC contract.
Jack Della Maddalena made his UFC debut in January 2022, defeating Pete Rodriguez via TKO in the first round.
In June 2022, Jack Della Maddalena won against Ramazan Emeev via TKO in the first round at UFC 275, earning him the Performance of the Night award.
Jack Della Maddalena continued his winning streak in November 2022 at UFC Fight Night: Nzechukwu vs. Cuțelaba, defeating Danny Roberts via technical knockout in the first round. This victory earned him his second straight Performance of the Night bonus.
Jack Della Maddalena secured a first-round submission win against Randy Brown at UFC 284 in February 2023, earning him another Performance of the Night award.
Jack Della Maddalena was scheduled to fight Sean Brady at UFC 290 in July 2023. However, Brady withdrew due to injury and his replacement, Josiah Harrell, was pulled out due to a medical condition, leading to the bout's cancellation.
Jack Della Maddalena won a split decision against Bassil Hafez at UFC Fight Night: Holm vs. Bueno Silva in July 2023. Both fighters were awarded the Fight of the Night bonus.
In September 2023, Jack Della Maddalena won a split decision against Kevin Holland at UFC Fight Night 227. Despite the split decision, all 16 media scorecards favored Della Maddalena.
As of March 2024, Jack Della Maddalena is ranked #5 in the UFC welterweight rankings.
Jack Della Maddalena defeated Gilbert Burns by technical knockout in the third round at UFC 299 in March 2024. This win earned him another Performance of the Night award.