Cancer is a collection of diseases characterized by uncontrolled cell growth and the potential to invade other parts of the body, distinguishing it from benign tumors. Symptoms vary but can include lumps, unusual bleeding, persistent cough, unexplained weight loss, and altered bowel habits; however, these symptoms are not exclusively indicative of cancer. There are over 100 different types of cancer that can affect humans.
Between 1950 and 2005, the cancer death rate (adjusting for size and age of the population) declined by five percent.
In 1971, US President Richard Nixon declared the "War on Cancer". Since then, the country has spent over $200 billion on cancer research.
In 1975, tracking of childhood cancer rates began in the United States. Death from childhood cancer decreased by half between 1975 and 2010.
In 1978, Susan Sontag published "Illness as Metaphor" while recovering from breast cancer treatment, ridiculing the idea that cancer was caused by a bad attitude.
In 1978, tracking of childhood cancer rates began in Europe. Between 1978 and 1997, rates of childhood cancer in Europe increased by 1.1% per year.
In 1990, deaths from cancer were 5.8 million worldwide, with increases primarily attributed to longer lifespans and lifestyle changes in the developing world.
Since 1990, there has been a decrease in lung cancer death rates in men in the United States, mirroring the decrease in smoking rates since the 1950s.
Between 1978 and 1997, rates of childhood cancer in Europe increased by 1.1% per year.
Since 1997, a variety of therapies using immunotherapy, which stimulates or helps the immune system to fight cancer, have come into use.
Between 1975 and 2002, the rates of childhood cancer in the United States increased by 0.6% per year.
Between the 1960s and 2004, the share of health expenditure devoted to cancer treatment has remained close to 5% in the US.
Between 1950 and 2005, the cancer death rate (adjusting for size and age of the population) declined by five percent.
In 2008, approximately 12.7 million cancers were diagnosed, excluding non-melanoma skin cancers and other non-invasive cancers.
As of 2010, the global total economic costs of cancer were estimated at US$1.16 trillion.
Between 1975 and 2010, death from childhood cancer decreased by half in the United States.
In 2010, nearly 7.98 million people died from cancer, accounting for approximately 16% of all deaths.
In 2012, approximately 165,000 children under the age of 15 were diagnosed with cancer.
In 2014, a meta-analysis found no significant relationship between the consumption of fruits and vegetables and the risk of cancer.
In 2014, a review found that supplements had no significant effect on cancer risk. Another review in 2014 concluded that vitamin D3 may decrease the risk of death from cancer, but concerns with the quality of the data were noted.
In 2015, approximately 90.5 million individuals worldwide were affected by cancer.
In 2015, the IARC reported that eating processed meat (e.g., bacon, ham, hot dogs, sausages) and, to a lesser degree, red meat was linked to some cancers.
In 2015, the total health care expenditure on cancer in the US was estimated to be $80.2 billion.
As of 2018, the most common cancers leading to death were lung cancer (1.76 million deaths), colorectal cancer (860,000 deaths), stomach cancer (780,000 deaths), liver cancer (780,000 deaths), and breast cancer (620,000 deaths).
In 2019, approximately 44% of all cancer deaths, which equates to about 4.5 million deaths, were attributed to known and preventable risk factors such as smoking, alcohol use, and high BMI.
In 2019, there was a significant increase in annual cancer cases by 23.6 million people, resulting in 10 million deaths worldwide. This represented a 26% increase in cases and a 21% increase in deaths over the previous decade.
In 2022, a study explored cancer risk in wild (non-domesticated) zoo mammals across 191 species and 110,148 individuals, demonstrating that cancer is a ubiquitous disease among mammals.
On December 2023, Nano Today published a groundbreaking discovery involving "NK cell-engaging nanodrones" for targeted cancer treatment.
In 2024, the global total economic costs of cancer were equivalent to $1.67 trillion.
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