Cancer is a collection of diseases characterized by the uncontrolled growth of abnormal cells, leading to the formation of tumors. Unlike benign tumors, cancerous tumors can invade nearby tissues and spread to distant parts of the body, a process called metastasis. There exist over 100 different types of cancer, each with unique characteristics and potential for harm. Early detection and treatment are crucial for improving outcomes and survival rates.
Between 1950 and 2005, the cancer death rate in the US declined by five percent.
In 1971, US President Richard Nixon declared the "war on cancer", leading to increased cancer research funding.
Between 1975 and 2002, rates of childhood cancer in the United States increased by 0.6% per year. Also, between 1975 and 2010, deaths from childhood cancer decreased by half in the United States.
Between 1978 and 1997, rates of childhood cancer in Europe increased by 1.1% per year.
In 1978, Susan Sontag published "Illness as Metaphor" while recovering from treatment for breast cancer, criticizing the idea that cancer could be caused by a bad attitude.
In 1990, deaths from cancer worldwide totaled 5.8 million.
Since 1990, lung cancer death rates in men in the United States decreased, following earlier decreases in smoking rates that began in the 1950s.
Between 1978 and 1997, rates of childhood cancer in Europe increased by 1.1% per year.
Since 1997, a variety of therapies using immunotherapy have been used to stimulate or help the immune system to fight cancer.
Between 1975 and 2002, rates of childhood cancer in the United States increased by 0.6% per year.
Between the 1960s and 2004, the share of health expenditure devoted to cancer treatment has remained close to 5%.
Between 1950 and 2005, the cancer death rate in the US declined by five percent, adjusting for size and age of the population.
In 2008, approximately 12.7 million cancer cases were diagnosed worldwide, excluding non-melanoma skin cancers and other non-invasive cancers.
As of 2010, the global total economic costs of cancer were estimated at US$1.16 trillion per year.
Between 1975 and 2010, the rate of death from childhood cancer decreased by half in the United States.
In 2010, nearly 7.98 million people died from cancer worldwide.
In 2012, approximately 165,000 children under the age of 15 were diagnosed with cancer.
A 2014 meta-analysis found no significant relationship between fruit and vegetable consumption and cancer risk.
In 2014, one review found that vitamin supplements had no significant effect on cancer risk. Another review concluded that vitamin D3 may decrease the risk of death from cancer, but concerns were noted about the quality of the data.
In 2015, approximately 90.5 million individuals globally were affected by cancer.
In 2015, the IARC reported that the consumption of processed meat, such as bacon, ham, hot dogs, and sausages, and to a lesser extent red meat, was linked to an increased risk of certain cancers.
In 2015, the total health care expenditure on cancer in the United States was estimated to be $80.2 billion.
In 2018, it was estimated that there were 18.1 million new cases of cancer and 9.6 million deaths globally.
In 2019, a GBD systematic analysis indicated that approximately 44% of all cancer deaths, or 4.5 million deaths, were due to known and preventable risk factors such as smoking, alcohol use, and high BMI.
In 2019, there was a significant increase of 23.6 million annual cancer cases worldwide, accompanied by 10 million deaths. This represented a rise of 26% in cases and 21% in deaths compared to the previous decade.
As of 2020, the cancers causing the most deaths globally were lung cancer (1.8 million), colorectal cancer (916,000), liver cancer (830,000), stomach cancer (769,000), and breast cancer (685,000).
A study published in 2022 explored cancer risk in non-domesticated zoo mammals, belonging to 191 species and 110,148 individuals, demonstrating that cancer is a ubiquitous disease among mammals and can emerge anywhere along the mammalian phylogeny. The study also highlighted that cancer risk is not uniformly distributed among mammals.
In 2024, the global total economic costs of cancer were equivalent to $1.67 trillion per year, based on 2010 estimates.
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