Measles is a highly contagious infectious disease caused by the measles virus. It is also known as morbilli, rubeola, red measles, and English measles. Critically, measles is vaccine-preventable. It's important to distinguish it from other diseases like rubella (German measles) and roseola, which are caused by different viruses.
In 1914, a statistician for the Prudential Insurance Company estimated from a survey of 22 countries that 1% of all deaths in the temperate zone were caused by measles. He also observed that 1–6% of cases of measles ended fatally, depending on age, social conditions, and pre-existing health conditions.
In 1954, the virus causing measles was isolated from a 13-year-old boy, David Edmonston, and adapted and propagated on chick embryo tissue culture.
In 1957, M.S. Bartlett first recognized the concept that the continued circulation of measles in a community depends on generating susceptible hosts, referring to the minimum number supporting measles as the critical community size (CCS).
The Advisory Committee on Immunization Practices (ACIP) recommends that all adult international travelers who do not have positive evidence of previous measles immunity receive two doses of MMR vaccine before traveling, although birth before 1957 is presumptive evidence of immunity.
In 1963, licensed vaccines to prevent measles became available.
In 1968, an improved measles vaccine became available.
In 1980, 2.6 million people died from measles.
Between 1985 and 1992, the death rate for measles cases reported in the U.S. was 0.2%.
Between 1987 and 2000, the case fatality rate across the United States was three deaths per 1,000 cases attributable to measles, or 0.3%.
In 1990, 545,000 people died due to measles.
In 1991, a measles outbreak in Philadelphia centered at the Faith Tabernacle Congregation resulted in over 1400 infections and nine children's deaths due to the church's discouragement of vaccination.
Between 1985 and 1992, the death rate for measles cases reported in the U.S. was 0.2%.
In 2019, 1,282 individual cases of measles were confirmed in 31 states, this is the greatest number of cases reported in the U.S. since 1992.
In 2024, a significant increase in measles cases in Europe occurred, with 127,350 being reported, which was the highest caseload in the region since 1997, representing a third of global measles cases. The major centre of the resurgent outbreak appeared to be Romania where 30,692 cases were reported.
Worldwide, measles fatalities fell 60% from an estimated 873,000 deaths in 1999 to 345,000 in 2005, thanks to a vaccination campaign led by partners in the Measles Initiative.
Between 1987 and 2000, the case fatality rate across the United States was three deaths per 1,000 cases attributable to measles, or 0.3%.
Between 2000 and 2017, vaccination efforts resulted in an 80% decrease in deaths from measles.
In 2000, measles as an endemic disease was eliminated from the United States, but continues to be reintroduced by international travelers.
In 2000, measles was declared eliminated as an endemic disease in the United States.
In 2000, the WHO established the Global Measles and Rubella Laboratory Network (GMRLN) to provide laboratory surveillance for measles, rubella, and congenital rubella syndrome.
In 2012, the number of deaths due to measles was 78% lower than in 2000 due to increased rates of immunization among UN member states.
From 2001 to 2011, there were 911 measles cases in the United States.
Prior to the death in Washington State, the last recorded measles fatality in the U.S. was in 2003. This highlights the severity of the 2015 case, making it the first in 12 years.
Between roughly 1855 and 2005, measles is estimated to have killed about 200 million people worldwide.
Worldwide, measles fatalities fell 60% from an estimated 873,000 deaths in 1999 to 345,000 in 2005, thanks to a vaccination campaign led by partners in the Measles Initiative.
From 2007 to 2017, the death rate in England and Wales occurred between two and three cases out of 10,000.
Estimates for 2008 indicate measles deaths fell further to 164,000 globally, with 77% of the remaining measles deaths in 2008 occurring within the Southeast Asian region.
From 2001 to 2011, there were 911 measles cases in the United States.
In 2011, German anti-vaccination campaigner Stefan Lanka offered €100,000 for proof that measles is caused by a virus. After being presented with the evidence, Lanka refused to accept it, leading to a legal battle. Neurologist Steven Novella called Lanka "a crank".
In 2011, the WHO estimated that 158,000 deaths were caused by measles.
In 2012, the number of deaths due to measles was 78% lower than in 2000 due to increased rates of immunization among UN member states.
In 2013–14, there were almost 10,000 measles cases in 30 European countries, with most cases occurring in unvaccinated individuals, predominantly in Germany, Italy, Netherlands, Romania, and United Kingdom.
Between October 2014 and March 2015, a measles outbreak in the German capital of Berlin resulted in at least 782 cases.
From 4 January, to 2 April 2015, there were 159 cases of measles reported to the CDC. Of those 159 cases, 111 (70%) were determined to have come from an earlier exposure in late December 2014. The outbreak originated from the Disneyland theme park in California and was held responsible for the infection of 147 people in seven U.S. states as well as Mexico and Canada.
By 2014, global vaccination programs had reduced the number of deaths from measles to 73,000.
In 2014 the CDC said endemic measles, rubella, and congenital rubella syndrome had not returned to the United States.
In 2014, an outbreak was initiated in Ohio when two unvaccinated Amish men harboring asymptomatic measles returned to the United States from missionary work in the Philippines, leading to 383 cases across nine counties.
In the spring of 2014, an estimated 8,500 measles cases were reported in the Vietnamese measles epidemic as of April 19, with 114 fatalities; as of 30 May, 21,639 suspected measles cases had been reported, with 142 measles-related fatalities.
Between October 2014 and March 2015, a measles outbreak in the German capital of Berlin resulted in at least 782 cases.
From 4 January, to 2 April 2015, there were 159 cases of measles reported to the CDC.
In 2015, a woman in Washington state died from pneumonia as a result of measles. She was the first measles fatality in the U.S. since 2003. The woman had been vaccinated but was taking immunosuppressant drugs.
In 2025, the first measles death since 2015 was reported.
In August 2016, at least 40 children died during a measles outbreak in the Naga Self-Administered Zone in Myanmar. The outbreak was likely caused by a lack of vaccination.
As a result of widespread vaccination, measles was declared eliminated from the Americas in 2016.
Data from 2016 to 2018 show that the most frequently detected measles virus genotypes are decreasing, suggesting that increasing global population immunity has decreased the number of chains of transmission.
In 2016, Brazil won a measles elimination certificate by the Pan American Health Organization.
In 2016, a record low of 4,400 measles cases were reported in Europe.
In 2016, the spread of measles had been interrupted in Brazil, with the last-known case twelve months earlier. This last case was in the state of Ceará.
In June 2017, the Maine Health and Environmental Testing Laboratory confirmed a measles case in Franklin County, marking the first case of measles in Maine in 20 years.
After being declared eliminated in 2016, measles cases reappeared in the Americas in 2017, 2018, 2019, and 2020.
As of 2017, approximately 85% of children worldwide had received their first dose of the measles vaccine.
Estimates for 2018 were slightly higher than that of 2017, when 124,000 deaths were reported due to measles infection globally.
From 2007 to 2017, the death rate in England and Wales occurred between two and three cases out of 10,000.
From 2017, a measles resurgence in Europe started to occur with numbers increasing in that year to 21,315 cases, with 35 deaths.
In 2017, a review of measles's reproductive number estimates provided a range of 3.7 to 203.3, which varies beyond the frequently cited range of 12 to 18.
In 2017, there were only two measles cases in Orthodox Jewish areas of Brooklyn.
In 2018, a measles case occurred in Portland, Oregon. As of July 2nd, 2018, 500 people were exposed, with 40 lacking immunity and being monitored by county health officials.
In October 2018, a measles outbreak began in Brooklyn, New York, with more than 200 cases reported. This outbreak continued until February 2019 and was linked to the Orthodox Jewish community.
A measles outbreak in 2018 resulted in well beyond 115,000 cases and over 1,200 deaths.
After being declared eliminated in 2016, measles cases reappeared in the Americas in 2017, 2018, 2019, and 2020.
As of 2018, measles remains a leading cause of vaccine-preventable deaths in the world.
Cases reported in the first three months of 2019 were 300% higher than in the first three months of 2018, with outbreaks in every region of the world, even in countries with high overall vaccination coverage where it spread among clusters of unvaccinated people.
Data from 2016 to 2018 show that the most frequently detected measles virus genotypes are decreasing, suggesting that increasing global population immunity has decreased the number of chains of transmission.
In 2018, 285 measles cases were centered on the Orthodox Jewish areas of Brooklyn, while there were only two cases in 2017.
In 2018, the measles vaccination rate in Samoa was 31 to 34%.
In 2018, there were 142,300 measles related deaths globally, of which most cases were reported from African and eastern Mediterranean regions.
By February 2019, the measles outbreak that began in Brooklyn in October 2018, was ongoing with over 200 reported cases. The outbreak was linked to the Orthodox Jewish community, with the initial exposure from an unvaccinated child visiting Israel.
In April 2019, New York Mayor Bill de Blasio declared a public health emergency because of "a huge spike" in measles cases, with 285 cases in Orthodox Jewish areas of Brooklyn in 2018 compared to only two cases in 2017, and 168 more cases in neighboring Rockland County. Nationally, there were 695 cases in 22 states.
From May 2019, a measles outbreak among the Malaysian Orang Asli sub-group of Batek people in the state of Kelantan caused the deaths of 15 from the tribe.
From January 1st to December 31st, 2019, 1,282 individual cases of measles were confirmed in 31 states in the United States. This was the greatest number of cases reported since 1992, with 128 hospitalizations and 61 reports of complications like pneumonia and encephalitis.
In December 2019, Samoa's measles vaccination rate reached an estimated 94% of the eligible population following a vaccination campaign. A state of emergency was declared from 17 November to 7 December.
After being declared eliminated in 2016, measles cases reappeared in the Americas in 2017, 2018, 2019, and 2020.
Cases reported in the first three months of 2019 were 300% higher than in the first three months of 2018, with outbreaks in every region of the world, even in countries with high overall vaccination coverage where it spread among clusters of unvaccinated people. In 2019, the total number of cases worldwide climbed to 869,770.
Following the end of the 2019 outbreak, reported cases fell to pre-outbreak levels.
In 2019 there were at least 1,241 cases of measles in the United States distributed across 31 states, with over three quarters in New York.
After being declared eliminated in 2016, measles cases reappeared in the Americas in 2017, 2018, 2019, and 2020.
In 2020, 13 cases of measles were reported.
In 2020, the number of measles cases reported was lower compared to 2019. According to the WHO, the COVID-19 pandemic hindered vaccination campaigns in at least 68 countries, including in countries that were experiencing outbreaks, which caused increased risk of additional cases.
In 2021, 49 cases of measles were reported.
In 2022, 121 cases of measles were reported.
In November 2024, the WHO and CDC reported that measles cases increased by 20% in 2023, primarily due to insufficient vaccine coverage in the world's poorest and conflict-affected regions, increasing from about 8.6 to 10.3 million cases.
In February 2024, the World Health Organization warned that more than half of the world was at risk of a measles outbreak due to COVID-19 pandemic-related disruptions.
In November 2024, the WHO and CDC reported that measles cases increased by 20% in 2023, primarily due to insufficient vaccine coverage in the world's poorest and conflict-affected regions, increasing from about 8.6 to 10.3 million cases.
In 2024, a measles outbreak was declared in the Bangsamoro region in the Philippines with at least 592 cases and 3 deaths.
In 2024, a significant increase in measles cases in Europe occurred, with 127,350 being reported, which was the highest caseload in the region since 1997, representing a third of global measles cases. The major centre of the resurgent outbreak appeared to be Romania where 30,692 cases were reported.
As of February 2025, a measles outbreak is ongoing amongst unvaccinated communities in Texas and New Mexico. On February 26, the first measles death since 2015 was reported to be that of an unvaccinated school-aged child in West Texas.
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