Enyel De Los Santos is a Dominican professional baseball pitcher currently playing for the Houston Astros in Major League Baseball (MLB). He debuted in MLB in 2018 with the Philadelphia Phillies and has since played for several teams, including the Pittsburgh Pirates, Cleveland Guardians, San Diego Padres, New York Yankees, Chicago White Sox, and Atlanta Braves. De Los Santos signed with the Seattle Mariners as an international free agent in 2014, marking the beginning of his professional baseball career.
On December 25, 1995, Enyel De Los Santos Polanco was born. He is a Dominican professional baseball pitcher.
On July 17, 2014, Enyel De Los Santos signed with the Seattle Mariners as an international free agent.
On November 12, 2015, Enyel De Los Santos was traded by the Mariners to the San Diego Padres in exchange for Joaquín Benoit.
On December 15, 2017, the Padres traded De Los Santos to the Philadelphia Phillies in exchange for Freddy Galvis.
On July 10, 2018, Enyel De Los Santos was promoted to the major leagues and made his MLB debut with the Phillies against the New York Mets, earning the win.
On August 9, 2020, Enyel De Los Santos was designated for assignment.
On May 4, 2021, De Los Santos had his contract selected back to the active roster.
On November 5, 2021, the Pirates outrighted De Los Santos to Triple-A Indianapolis and removed him from their 40-man roster.
On December 1, 2021, De Los Santos signed a minor league contract with an invitation to spring training with the Cleveland Guardians.
On November 17, 2023, the Guardians traded De Los Santos to the Padres in exchange for Scott Barlow.
On July 30, 2024, the Padres traded De Los Santos and Thomas Balboni Jr. to the New York Yankees in exchange for Brandon Lockridge.
On August 17, 2024, De Los Santos was claimed off waivers by the Chicago White Sox.
On December 15, 2024, De Los Santos signed a minor league contract with the Atlanta Braves.
On August 7, 2025, De Los Santos signed a major league contract with the Houston Astros.
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