Tyshun Raequan "Deebo" Samuel Sr. (born January 15, 1996) is an American football wide receiver for the San Francisco 49ers of the National Football League (NFL). He played college football for the South Carolina Gamecocks and was selected by the 49ers in the second round of the 2019 NFL draft. In 2021, he was selected to the Pro Bowl and received first-team All-Pro honors.
On November 5, 2017, Samuel announced that he would be returning for his senior season. Samuel finished the 2018 season with 882 yards receiving and 11 touchdowns. His best game of the season came against Clemson, where he caught 10 passes for 210 yards and three touchdowns. He chose not to play in the Gamecocks' bowl game, the 2018 Belk Bowl. He was later selected to play in the 2019 Senior Bowl.
Samuel was selected by the San Francisco 49ers in the second round (36th overall) of the 2019 NFL draft. He signed a four-year contract with the 49ers on July 25, 2019.
Samuel was placed on the non-football injury list at the start of training camp on July 28, 2020. He was activated on September 5, 2020, but was placed on injured reserve on September 12. He was activated on October 3. He was placed on the reserve/COVID-19 list by the team on November 4, and activated two days later. In Week 12 against the Rams, he had 11 receptions for 133 receiving yards in the 23–20 victory. Samuel finished the 2020 season with 33 receptions for 391 receiving yards and one receiving touchdown.
During the 2022 offseason, it was reported that Samuel requested to be traded; however, he reported to training camp and ultimately, on July 31, 2022, signed a three-year, $73.5 million contract extension with $58.1 million guaranteed.